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Article

Preliminary analysis of the FAM174A gene suggests it lacks a strong association with equine metabolic syndrome in ponies.

Domestic animal endocrinology - 1 Jul 2020

Cash C M, Fitzgerald D M, Spence R J, de Laat M A

Abstract excerpt

Equine metabolic syndrome (EMS) describes a group of risk factors, including obesity and insulin dysregulation (hyperinsulinemia and/or insulin resistance), that can lead to the development of the debilitating hoof disease laminitis. Although the underlying mechanisms of EMS are not fully understood, a genetic component has been reported, and an 11 guanine polymorphism located at the FAM174A gene has been...

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PMID: 32169753
DOI: 10.1016/j.domaniend.2020.106439

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