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Article

Induction of autophagy and suppression of type I IFN secretion by CSFV

11 Mar 2020

Abstract excerpt

Macroautophagy/autophagy plays an essential role in cellular responses to pathogens. However, the precise mechanisms and signaling pathways that modulate cellular autophagy in classical swine fever virus (CSFV)-infected host cells have not been confirmed. In this study, we showed that CSFV infection inhibits the phosphorylation of MTOR (mechanistic target of rapamycin kinase), subsequently leading to autophagy...

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PMID: 32160078
DOI: 10.1080/15548627.2020.1739445

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