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Article

Wnt-3a Induces Epigenetic Remodeling in Human Dental Pulp Stem Cells

7 Mar 2020

Abstract excerpt

Dental pulp stem cells (DPSCs) from adult teeth show the expression of a very complete repertoire of stem pluripotency core factors and a high plasticity for cell reprogramming. Canonical Wnt and Notch signaling pathways regulate stemness and the expression of pluripotency core factors in DPSCs, and even very short-term (48 h) activations of the Wnt pathway induce a profound remodeling of DPSCs at the physiologic...

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PMID: 32156036
DOI: 10.3390/cells9030652

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