Article
Simplification of Natural β-Carboline Alkaloids to Obtain Indole Derivatives as Potent Fungicides against Rice Sheath Blight.
Molecules (Basel, Switzerland) - 6 Mar 2020
Zeng Jie, Zhang Zhijun, Zhu Qi, Jiang Zhiyan, Zhong Guohua
Abstract excerpt
The increasing resistance of rice sheath blight caused by Rhizoctonia solani highlights the need for highly effective and environmentally benign agents. Natural β-carboline alkaloids were simplified to obtain a series of indole derivatives, and their fungicidal activity and preliminary mode of action against R. solani were also evaluated. The initial hit indole (7) displayed significant fungicidal activity with...
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