Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene discoveries in autism are biased towards comorbidity with intellectual disability.

Journal of medical genetics - 1 Sept 2020

Jensen Matthew, Smolen Corrine, Girirajan Santhosh

Abstract excerpt

BACKGROUND: Autism typically presents with highly heterogeneous features, including frequent comorbidity with intellectual disability (ID). The overlap between these phenotypes has confounded the diagnosis and discovery of genetic factors associated with autism. We analysed pathogenic de novo genetic variants in individuals with autism who had either ID or normal cognitive function to determine whether genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autism Spectrum Disorder
Share to DNA Copy Number Variations
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intellectual Disability

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 32152248
DOI: 10.1136/jmedgenet-2019-106476
PMCID: PMC7483239

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene discoveries in autism are biased towards comorbidity with intellectual disability.PMID 32152248Read ↗

Gene discoveries in autism are biased towards comorbidity with intellectual disabilitySemantic proximity Read ↗

The contribution of de novo coding mutations to autism spectrum disorder.Semantic proximity Read ↗

Comorbidities associated with genetic abnormalities in children with intellectual disability.Semantic proximity Read ↗

Recent Advances in Understanding the Genetic Architecture of Autism.Semantic proximity Read ↗

Genetic research in autism spectrum disorders.Semantic proximity Read ↗

Etiological heterogeneity in autism spectrum disorders: more than 100 genetic and genomic disorders and still counting.Semantic proximity Read ↗

The genetics of autism: key issues, recent findings, and clinical implications.Semantic proximity Read ↗

Current knowledge on the genetics of autism and propositions for future research.Semantic proximity Read ↗

Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general populationSemantic proximity Read ↗

Genomic Patterns of De Novo Mutation in Simplex Autism.Semantic proximity Read ↗

Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci.Semantic proximity Read ↗

Genetic Advances in Autism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.