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Article

CYP27B1 as an instrument gene to investigate the causal relationship between vitamin D deficiency and obesity: a family-based study.

European journal of clinical nutrition - 1 May 2020

Yu Songcheng, Feng Yinhua, Qu Chenling, Huo Wenqian, Mao Zhenxing, Wang Chongjian, Li Wenjie, Li Xing

Abstract excerpt

OBJECTIVES: Vitamin D deficiency was associated with obesity. However, the causal relationship remains controversial. We hypothesized that there would be family-based associations in both vitamin D deficient families and obese families for the SNPs associated with vitamin D deficiency, if vitamin D deficiency was a causal factor of obesity. We aimed to investigate the family-based association of SNPs in CYP27B1...

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PMID: 32127688
DOI: 10.1038/s41430-020-0594-7

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