Article
An eQTL in the cystathionine beta synthase gene is linked to osteoporosis in laying hens.
Genetics, selection, evolution : GSE - 24 Feb 2020
De Koning Dirk-Jan, Dominguez-Gasca Nazaret, Fleming Robert H, Gill Andrew, Kurian Dominic, Law Andrew, McCormack Heather A, Morrice David, Sanchez-Rodriguez Estefania, Rodriguez-Navarro Alejandro B, Preisinger Rudolf, Schmutz Matthias, Šmídová Veronica, Turner Frances, Wilson Peter W, Zhou Rongyan, Dunn Ian C
Abstract excerpt
BACKGROUND: Skeletal damage is a challenge for laying hens because the physiological adaptations required for egg laying make them susceptible to osteoporosis. Previously, we showed that genetic factors explain 40% of the variation in end of lay bone quality and we detected a quantitative trait locus (QTL) of large effect on chicken chromosome 1. The aim of this study was to combine data from the commercial...
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