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Article

Inhibition of Porphyromonas gulae and periodontal disease in dogs by a combination of clindamycin and interferon alpha.

Scientific reports - 20 Feb 2020

Nomura Ryota, Inaba Hiroaki, Yasuda Hidemi, Shirai Mitsuyuki, Kato Yukio, Murakami Masaru, Iwashita Naoki, Shirahata So, Yoshida Sho, Matayoshi Saaya, Yasuda Junya, Arai Nobuaki, Asai Fumitoshi, Matsumoto-Nakano Michiyo, Nakano Kazuhiko

Abstract excerpt

Porphyromonas gulae is a major periodontal pathogen in dogs, which can be transmitted to their owners. A major virulence factor of P. gulae consists of a 41-kDa filamentous appendage (FimA) on the cell surface, which is classified into three genotypes: A, B, and C. Thus far, inhibition of periodontal disease in dogs remains difficult. The present study assessed the inhibitory effects of a combination of...

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Identifiers

PMID: 32080231
DOI: 10.1038/s41598-020-59730-9
PMCID: PMC7033253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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