Article
Signature patterns in region V4 of small ruminant lentivirus surface protein in sheep and goats.
Virus research - 15 Apr 2020
González Méndez Ana Silvia, Cerón Téllez Fernando, Tórtora Pérez Jorge Luis, Martínez Rodríguez Humberto Alejandro, García Flores María Martha, Ramírez Álvarez Hugo
Abstract excerpt
The env gene in Small Ruminant Lentiviruses (SRLV) encodes the surface glycoprotein (SU) that divides into conserved (C1-C4) and variable regions (V1-V5). SRLV region V4 has been found to be homologous to the V3 region of human lentivirus (HIV). HIV V3 is responsible for tropism and the development of nervous clinical patterns when there is a tendency to conserve amino acids in specific "signature pattern"...
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