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Upregulated lncRNA UCA1 inhibits trophoblast cell invasion and proliferation by downregulating JAK2

17 Feb 2020

Abstract excerpt

Numerous studies have suggested that urothelial cancer-associated 1 (UCA1) acts as a suppressor gene affecting cell proliferation and migration. However, the biological role and the potential mechanism of UCA1 in the progression of pre-eclampsia (PE) remains unclear. The UCA1 level was markedly upregulated in PE pregnancies relative to non-PE ones in GSE75010 and tissues. A higher body mass index (BMI), maximum...

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PMID: 32067230
DOI: 10.1002/jcp.29643

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