Male origin microchimerism and ovarian cancer

Abstract excerpt

BACKGROUND: Reduced risk of ovarian cancer is commonly ascribed to reduced exposure to endogenous hormones during pregnancy, using oral contraceptives or not using hormone replacement therapy. However, exposure to hormones alone account for less than half of all cases. Many women carry small amounts of male cells-known as male origin microchimerism-in their circulation and remarkable impacts of these cells on...

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• Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
• Share to Prenatal Screening and Diagnostics
• Share to Sperm and Testicular Function