Computational Identification of the Proteins Associated With Quorum Sensing and Biofilm Formation in Mycobacterium tuberculosis

Abstract excerpt

With prolonged therapy and increased instances of drug resistance, tuberculosis is viewed as a serious infectious disease causing high mortality. Emerging concepts in M. tuberculosis pathogenicity include biofilm formation, which endows bacterial survival in the host for a long time. In order to tackle chronic tuberculosis infection, a detailed understanding of the bacterial survival mechanisms is crucial. Using...

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