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Article

Differential significance of molecular subtypes which were classified into EGFR exon 19 deletion on the first line afatinib monotherapy.

BMC cancer - 6 Feb 2020

Tokudome Nahomi, Koh Yasuhiro, Akamatsu Hiroaki, Fujimoto Daichi, Okamoto Isamu, Nakagawa Kazuhiko, Hida Toyoaki, Imamura Fumio, Morita Satoshi, Yamamoto Nobuyuki

Abstract excerpt

BACKGROUND: Epidermal growth factor receptor (EGFR)-sensitizing mutation, exon 19 deletion consists of several molecular variants. Influences of these variants on clinical response to EGFR tyrosine kinase inhibitors remain elusive. METHODS: West Japan Oncology Group 8114LTR is a prospective, multi-institutional biomarker study. Treatment naïve, advanced non-small-cell lung cancer patients with EGFR-sensitizing...

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Identifiers

PMID: 32028909
DOI: 10.1186/s12885-020-6593-1
PMCID: PMC7006223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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