Article
Food Intervention with Folate Reduces TNF-α and Interleukin Levels in Overweight and Obese Women with the MTHFR C677T Polymorphism: A Randomized Trial.
Nutrients - 30 Jan 2020
Lisboa Jéssica Vanessa de Carvalho, Ribeiro Marina Ramalho, Luna Rafaella Cristhine Pordeus, Lima Raquel Patrícia Ataíde, Nascimento Rayner Anderson Ferreira do, Monteiro Mussara Gomes Cavalcante Alves, Lima Keylha Querino de Farias, Fechine Carla Patrícia Novaes Dos Santos, Oliveira Naila Francis Paulo de, Persuhn Darlene Camati, Veras Robson Cavalcante, Gonçalves Maria da Conceição Rodrigues, Ferreira Flávia Emília Leite de Lima, Lima Roberto Teixeira, Silva Alexandre Sérgio da, Diniz Alcides da Silva, Almeida Aléssio Tony Cavalcanti de, Moraes Ronei Marcos de, Junior Eliseu Verly, Costa Maria José de Carvalho
Abstract excerpt
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism associated with body fat accumulation could possibly trigger an inflammatory process by elevating homocysteine levels and increasing cytokine production, causing several diseases. This study aimed to evaluate the effects of food intervention, and not folate supplements, on the levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and...
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