Article
Safety and Efficacy of 8 Weeks Ledipasvir/Sofosbuvir for Chronic Hepatitis C Genotype 4 in Children Aged 4-10 Years.
The Journal of pediatrics - 1 Apr 2020
Behairy Behairy E, El-Araby Hanaa A, El-Guindi Mohamed A, Basiouny Hosam-Eldin M, Fouad Ola A, Ayoub Bassam A, Marei Ayman M, Sira Mostafa M
Abstract excerpt
OBJECTIVE: To evaluate the safety and efficacy of shortened 8-week regimen of ledipasvir/sofosbuvir (LED/SOF) combination therapy in treatment-naïve children without cirrhosis aged 4-10 years of age with chronic hepatitis C virus (HCV) infection. STUDY DESIGN: This observational single arm prospective study included 30 treatment-naïve children (20 males) with proved chronic HCV fulfilling inclusion criteria....
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