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Article

Postnatal development of skeletal muscle in pigs with intrauterine growth restriction: morphofunctional phenotype and molecular mechanisms.

Journal of anatomy - 1 May 2020

Felicioni Fernando, Pereira Andreia D, Caldeira-Brant Andre L, Santos Thais G, Paula Thais M D, Magnabosco Diogo, Bortolozzo Fernando P, Tsoi Stephen, Dyck Michael K, Dixon Walter, Martinelli Patricia M, Jorge Erika C, Chiarini-Garcia Helio, Almeida Fernanda R C L

Abstract excerpt

Intrauterine growth restriction (IUGR) is a serious condition which impairs the achievement of the fetus' full growth potential and occurs in a natural and severe manner in pigs as a result of placental insufficiency. Reduced skeletal muscle mass in the fetus with IUGR persists into adulthood and may contribute to increased metabolic disease risk. To investigate skeletal muscle postnatal development,...

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Identifiers

PMID: 31997379
DOI: 10.1111/joa.13152
PMCID: PMC7163581

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