Article
Chromosome 15q BP3 to BP5 deletion is a likely locus for speech delay and language impairment: Report on a four-member family and an unrelated boy.
Molecular genetics & genomic medicine - 1 Apr 2020
Pavone Piero, Ruggieri Martino, Marino Simona D, Corsello Giovanni, Pappalardo Xena, Polizzi Agata, Parano Enrico, Romano Catia, Marino Silvia, Praticò Andrea Domenico, Falsaperla Raffaele
Abstract excerpt
BACKGROUND: Deletions in chromosome 15q13 have been reported both in healthy people and individuals with a wide range of behavioral and neuropsychiatric disturbances. Six main breakpoint (BP) subregions (BP1-BP6) are mapped to the 15q13 region and three further embedded BP regions (BP3-BP5). The deletion at BP4-BP5 is the rearrangement most frequently observed compared to other known deletions in BP3-BP5 and...
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