Article
Genetic cancer predisposition syndromes among older adults.
Journal of geriatric oncology - 1 Sept 2020
Chavarri-Guerra Yanin, Slavin Thomas P, Longoria-Lozano Ossian, Weitzel Jeffrey N
Abstract excerpt
Earlier age at onset is one characteristic of hereditary cancer syndromes, so most studies of genetic testing have focused on young patients with cancer. However, recent studies of multigene panel tests in unselected cancer populations have detected a considerable proportion of older patients with germline pathogenic variants (PVs) in cancer susceptibility genes. As the number of older patients with cancer...
Topics
- Aged
- Breast Neoplasms
- Genetic Counseling
- Genetic Predisposition to Disease
- Genetic Testing
- Humans
- Male
- Neoplastic Syndromes, Hereditary
