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Article

CircPTK2 (hsa_circ_0005273) as a novel therapeutic target for metastatic colorectal cancer

23 Jan 2020

Abstract excerpt

BACKGROUND: As a novel class of noncoding RNAs, circRNAs have been recently identified to regulate tumorigenesis and aggressiveness. However, the function of circRNAs in colorectal cancer (CRC) metastasis remains unclear. We aimed to identify circRNAs that are upregulated in CRC tissues from patients and study their function in CRC metastasis. METHODS: We compared six pairs of CRC tissues and their matched...

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PMID: 31973707
DOI: 10.1186/s12943-020-1139-3

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