Article
Harmonizing behavioral outcomes across studies, raters, and countries: application to the genetic analysis of aggression in the ACTION Consortium.
Journal of child psychology and psychiatry, and allied disciplines - 1 Jul 2020
Luningham Justin M, Hendriks Anne M, Krapohl Eva, Fung Ip Hill, van Beijsterveldt Catharina E M, Lundström Sebastian, Vuoksimaa Eero, Korhonen Tellervo, Lichtenstein Paul, Plomin Robert, Pulkkinen Lea, Rose Richard J, Kaprio Jaakko, Bartels Meike, Boomsma Dorret I, Lubke Gitta H
Abstract excerpt
BACKGROUND: Aggression in children has genetic and environmental causes. Studies of aggression can pool existing datasets to include more complex models of social effects. Such analyses require large datasets with harmonized outcome measures. Here, we made use of a reference panel for phenotype data to harmonize multiple aggression measures in school-aged children to jointly analyze data from five large twin...
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