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Article

Acquisition, transmission and strain diversity of human gut-colonizing crAss-like phages.

Nature communications - 15 Jan 2020

Siranosian Benjamin A, Tamburini Fiona B, Sherlock Gavin, Bhatt Ami S

Abstract excerpt

CrAss-like phages are double-stranded DNA viruses that are prevalent in human gut microbiomes. Here, we analyze gut metagenomic data from mother-infant pairs and patients undergoing fecal microbiota transplantation to evaluate the patterns of acquisition, transmission and strain diversity of crAss-like phages. We find that crAss-like phages are rarely detected at birth but are increasingly prevalent in the infant...

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Identifiers

PMID: 31941900
DOI: 10.1038/s41467-019-14103-3
PMCID: PMC6962324

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