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Article

Role of microRNAs in antiviral responses to dengue infection

2 Jan 2020

Abstract excerpt

Dengue virus (DENV) is the etiological agent of dengue fever. Severe dengue could be fatal and there is currently no effective antiviral agent or vaccine. The only licensed vaccine, Dengvaxia, has low efficacy against serotypes 1 and 2. Cellular miRNAs are post-transcriptional regulators that could play a role in direct regulation of viral genes. Host miRNA expressions could either promote or repress viral...

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PMID: 31898495
DOI: 10.1186/s12929-019-0614-x

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