Article
Genotyping of Malaysian G6PD-deficient neonates by reverse dot blot flow-through hybridisation.
Journal of human genetics - 1 Mar 2020
Alina M F, Azma R Z, Norunaluwar J, Azlin I, Darnina A J, Cheah F C, Noor-Farisah A R, Siti-Hawa A A, Danny X R K, Zulkifli Noor-Fadzilah, Ainoon O
Abstract excerpt
G6PD deficiency is the commonest enzyme deficiency found in humans. Current diagnostic methods lack sensitivity to detect all cases of G6PD deficiency. We evaluated the reverse dot blot flow-through hybridisation assay designed to detect simultaneously multiple known G6PD mutations in a group of Malaysian neonates. Archival DNA samples from 141 G6PD-deficient neonates were subjected to reverse dot blot...
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