Article
Human papillomavirus genotypes and P16INK4A expression in squamous penile carcinoma in Mexican patients.
BMC infectious diseases - 19 Dec 2019
Martínez-Bailón Cecilia, Mantilla-Morales Alejandra, Méndez-Matías Galo, Alvarado-Cabrero Isabel, Maldonado-Rodríguez Rogelio, Quintero-Becerra Joel, Arias-Flores Rafael, Piña-Sánchez Patricia
Abstract excerpt
BACKGROUND: Approximately 50% of cases of penile carcinoma (PeCa), a rare neoplasm worldwide, are associated with human papillomavirus (HPV). However, the detection of HPV-DNA is not sufficient to consider it the etiological factor in the development of this type of cancer. Currently, the overexpression of P16INK4A is used as a surrogate biomarker of HPV carcinogenesis. Information on PeCa in Mexico is scarce,...
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