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Expression profile analysis identifies IER3 to predict overall survival and promote lymph node metastasis in tongue cancer

21 Nov 2019

Abstract excerpt

BACKGROUND: Lymph node metastasis is one of the most important factors affecting the prognosis of tongue cancer, and the molecular mechanism regulating lymph node metastasis of tongue cancer is poorly known. METHODS: The gene expression dataset GSE2280 and The Cancer Genome Atlas (TCGA) tongue cancer dataset were downloaded. R software was used to identify the differentially expressed hallmark gene sets and...

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PMID: 31832020
DOI: 10.1186/s12935-019-1028-2

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