Article
Association of vitamin D receptor TaqI and ApaI genetic polymorphisms with nephrolithiasis and end stage renal disease: a meta-analysis.
BMC medical genetics - 10 Dec 2019
Hussain Tajamul, Naushad Shaik M, Ahmed Anwar, Alamery Salman, Mohammed Arif A, Abdelkader Mohamed O, Alkhrm Nasser Abobakr Nasser
Abstract excerpt
BACKGROUND: The deficiency of vitamin D receptor (VDR) or its ligand, vitamin D3, is linked to the development of renal diseases. The TaqI (rs731236) and ApaI (rs7975232) polymorphisms of VDR gene are widely studied for their association with renal disease risk. However, studies have largely been ambiguous. METHODS: Meta-analysis was carried out to clarify the association of TaqI (2777 cases and 3522 controls)...
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