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Article

Pretreatment HIV drug resistance spread within transmission clusters in Mexico City.

The Journal of antimicrobial chemotherapy - 1 Mar 2020

Matías-Florentino Margarita, Chaillon Antoine, Ávila-Ríos Santiago, Mehta Sanjay R, Paz-Juárez Héctor E, Becerril-Rodríguez Manuel A, Del Arenal-Sánchez Silvia J, Piñeirúa-Menéndez Alicia, Ruiz Verónica, Iracheta-Hernández Patricia, Macías-González Israel, Tena-Sánchez Jehovani, Badial-Hernández Florentino, González-Rodríguez Andrea, Reyes-Terán Gustavo

Abstract excerpt

BACKGROUND: Pretreatment HIV drug resistance (HIVDR) to NNRTIs has consistently increased in Mexico City during the last decade. OBJECTIVES: To infer the HIV genetic transmission network in Mexico City to describe the dynamics of the local HIV epidemic and spread of HIVDR. PATIENTS AND METHODS: HIV pol sequences were obtained by next-generation sequencing from 2447 individuals before initiation of ART at the...

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Identifiers

PMID: 31819984
DOI: 10.1093/jac/dkz502
PMCID: PMC7021100

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