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Article

The intestinal microbiota regulates host cholesterol homeostasis

27 Nov 2019

Abstract excerpt

BACKGROUND: Management of blood cholesterol is a major focus of efforts to prevent cardiovascular diseases. The objective of this study was to investigate how the gut microbiota affects host cholesterol homeostasis at the organism scale. RESULTS: mice using broad-spectrum antibiotics. Measurement of plasma cholesterol levels as well as cholesterol synthesis and fluxes by complementary approaches showed that the...

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PMID: 31775890
DOI: 10.1186/s12915-019-0715-8

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