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Article

A histone deacetylase, MoHOS2 regulates asexual development and virulence in the rice blast fungus.

Journal of microbiology (Seoul, Korea) - 1 Dec 2019

Lee Jongjune, Lee Jae-Joon, Jeon Junhyun

Abstract excerpt

Histone acetylation/deacetylation represent a general and efficient epigenetic mechanism through which fungal cells control gene expression. Here we report developmental requirement of MoHOS2-mediated histone deacetylation (HDAC) for the rice blast fungus, Magnaporthe oryzae. Structural similarity and nuclear localization indicated that MoHOS2 is an ortholog of Saccharomyces cerevisiae Hos2, which is a member of...

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PMID: 31758396
DOI: 10.1007/s12275-019-9363-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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