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Article

Novel mutations in the QRDR region gyrA gene in multidrug-resistance Corynebacterium spp. isolates from intravenous sites.

Antonie van Leeuwenhoek - 1 Apr 2020

Ramos Juliana Nunes, Valadão Talita Bernardo, Baio Paulo Victor Pereira, Mattos-Guaraldi Ana Luiza, Vieira Verônica Viana

Abstract excerpt

The resistance to fluoroquinolones in corynebacteria is due to mutations occurring in the quinolone-resistance-determining region (QRDR) of the gyrA gene encoding the enzyme gyrase A subunit. In recent years we can observe an increasing number of infections caused by multidrug-resistant Corynebacterium striatum, Corynebacterium jeikeium and Corynebacterium urealyticum, including wide range of disorders, such as...

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Identifiers

PMID: 31736013
DOI: 10.1007/s10482-019-01353-w
PMCID: PMC7089888

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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