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Article

A phenotype-directed chemical screen identifies ponalrestat as an inhibitor of the plant flavin monooxygenase YUCCA in auxin biosynthesis.

The Journal of biological chemistry - 27 Dec 2019

Zhu Ying, Li Hong-Jiang, Su Qi, Wen Jing, Wang Yuefan, Song Wen, Xie Yinpeng, He Wenrong, Yang Zhen, Jiang Kai, Guo Hongwei

Abstract excerpt

Plant development is regulated by both synergistic and antagonistic interactions of different phytohormones, including a complex crosstalk between ethylene and auxin. For instance, auxin and ethylene synergistically control primary root elongation and root hair formation. However, a lack of chemical agents that specifically modulate ethylene or auxin production has precluded precise delineation of the...

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PMID: 31732559
DOI: 10.1074/jbc.RA119.010480
PMCID: PMC6937590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A phenotype-directed chemical screen identifies ponalrestat as an inhibitor of the plant flavin monooxygenase YUCCA in auxin biosynthesis.PMID 31732559Read ↗

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