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Article

Value of pre-therapy 18F-FDG PET/CT radiomics in predicting EGFR mutation status in patients with non-small cell lung cancer.

European journal of nuclear medicine and molecular imaging - 1 May 2020

Zhang Jianyuan, Zhao Xinming, Zhao Yan, Zhang Jingmian, Zhang Zhaoqi, Wang Jianfang, Wang Yingchen, Dai Meng, Han Jingya

Abstract excerpt

PURPOSE: To assess the predictive power of pre-therapy 18F-FDG PET/CT-based radiomic features for epidermal growth factor receptor (EGFR) mutation status in non-small cell lung cancer. METHODS: Two hundred and forty-eight lung cancer patients underwent pre-therapy diagnostic 18F-FDG PET/CT scans and were tested for genetic mutations. The LIFEx package was used to extract 47 PET and 45 CT radiomic features...

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PMID: 31728587
DOI: 10.1007/s00259-019-04592-1

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