Article
Clinical Outcomes of Different Generations of EGFR Tyrosine Kinase Inhibitors in Advanced Lung Adenosquamous Carcinoma.
Molecular diagnosis & therapy - 1 Dec 2019
Hu Minjuan, Zhang Bo, Xu Jianlin, Wang Shuyuan, Zhao Yiming, Zhang Lele, Han Baohui
Abstract excerpt
OBJECTIVES: The role of targeted therapy in patients with lung adenosquamous carcinoma (ASC) has been controversial and it was unclear whether a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) could improve outcomes. This study was designed to evaluate the efficacy of different generations of EGFR TKI therapy in ASC patients with sensitive EGFR mutations. METHODS: Patients...
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