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Study on amniotic fluid metabolism in the second trimester of Trisomy 21

10 Nov 2019

Abstract excerpt

BACKGROUND: Trisomy 21 is a common aneuploid condition in humans and accounts for approximately one quarter of all aneuploid live births. To date, early diagnosis of Trisomy 21 remains a challenging task. Metabolomics may prove an innovative tool to study the early pathophysiology of Trisomy 21 at a functional level. METHODS: Ultra-performance liquid chromatography coupled with mass spectrometer (UPLC-MS) was...

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PMID: 31709651
DOI: 10.1002/jcla.23089

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