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Article

Comprehensive circular RNA profiling identifies CircFAM120A as a new biomarker of hypoxic lung adenocarcinoma

1 Sept 2019

Abstract excerpt

BACKGROUND: Hypoxia is crucial in the initiation and progression of tumor metastasis. Circular RNAs (CircRNAs) comprise a novel group of non-coding, RNase R resistant and regulatory RNAs which are generated by 'back-splicing' processes. However, the characterization and function of circRNAs in hypoxic cancer cells remain unknown. METHODS: High throughput RNA-seq assay was performed in lung adenocarcinoma cells...

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PMID: 31700878
DOI: 10.21037/atm.2019.08.79

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