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Article

The composition and functional protein subsystems of the human nasal microbiome in granulomatosis with polyangiitis: a pilot study

22 Oct 2019

Abstract excerpt

Abstract Background Ear, nose and throat involvement in granulomatosis with polyangiitis (GPA) is frequently the initial disease manifestation. Previous investigations have observed a higher prevalence ofStaphylococcus aureusin patients with GPA, and chronic nasal carriage has been linked with an increased risk of disease relapse. In this cross-sectional study, we investigated changes in the nasal microbiota...

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PMID: 31640771
DOI: 10.1186/s40168-019-0753-z

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