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Identification and characterization of circRNAs as competing endogenous RNAs for miRNA-mRNA in colorectal cancer

19 Sept 2019

Abstract excerpt

BACKGROUND: Recent studies showed that circRNAs are involved in the biological process of some human cancers. However, little is known about their functions in colorectal cancer (CRC). METHODS: Here we first revealed the expression profiles of circRNAs in the CRC tissues and the adjacent non-tumorous tissues using high-throughput sequencing. The sequence feature, chromosome location, alternative splicing and...

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PMID: 31579577
DOI: 10.7717/peerj.7602

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