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Article

Genetic alterations of epithelial polarity genes are associated with loss of polarity in invasive breast cancer

2 Oct 2019

Abstract excerpt

Breast cancer remains a leading cause of cancer-related death for women. The stepwise development of breast cancer through preinvasive to invasive disease is associated with progressive disruption of cellular and tissue organization. Apical-basal polarity is thought to be a barrier to breast cancer development, but the extent and potential mechanisms that contribute to disrupted polarity are incompletely...

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PMID: 31577845
DOI: 10.1002/ijc.32691

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