Whole Genome Sequencing for Surveillance of Diphtheria in Low Incidence Settings

Abstract excerpt

Corynebacterium diphtheriae is a relatively rare pathogen in most Western countries. While toxin producing strains can cause pharyngeal diphtheria with potentially fatal outcomes, the more common presentation is wound infections. The diphtheria toxin is encoded on a prophage and can also be carried by Corynebacterium ulcerans and Corynebacterium pseudotuberculosis. Currently, across Europe, infections are mainly...

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