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Article

Peptidoglycan-Associated Cyclic Lipopeptide Disrupts Viral Infectivity

23 Aug 2019

Abstract excerpt

In this article, we consider a role for bacteria in shaping coronavirus infection. Taking cues from studies of enteric viruses, we initially investigated how bacterial surface components might improve CoV infection. Instead, we found that peptidoglycan-associated surfactin is a potent viricidal compound that disrupts virion integrity with broad activity against enveloped viruses. Our results indicate that...

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Share to SARS-CoV-2 and COVID-19 Research
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PMID: 31462558
DOI: 10.1128/jvi.01282-19

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