Identification of seven-gene signature for prediction of lung squamous cell carcinoma

Abstract excerpt

Background and aim: Lung squamous cell carcinoma (LUSC), is a pathological subtype of lung cancer, accounting for 30% of the lung cancers. A reliable model was constructed, based on the whole gene expression profiles, to predict the prognosis of patients with LUSC. Methods: The RNA-Seq data of LUSC was downloaded from the TCGA database, and differentially expressed genes ( p <0.05, |log2fold change| >1) were...

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