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Sperm Proteome Analysis and Identification of Fertility-Associated Biomarkers in Unexplained Male Infertility

11 Jul 2019

Abstract excerpt

Up to 30% of men with normal semen parameters suffer from infertility and the reason for this is unknown. Altered expression of sperm proteins may be a major cause of infertility in these men. Proteomic profiling was performed on pooled semen samples from eight normozoospermic fertile men and nine normozoospermic infertile men using LC-MS/MS. Furthermore, key differentially expressed proteins (DEPs) related to...

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PMID: 31336797
DOI: 10.3390/genes10070522

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