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Microbiota-Related Changes in Unconjugated Fecal Bile Acids Are Associated With Naturally Occurring, Insulin-Dependent Diabetes Mellitus in Dogs

27 Jun 2019

Abstract excerpt

Changes in the gut microbiota have been linked to human metabolic diseases, including diabetes mellitus (DM). The bidirectional effects between intestinal microbiota and bile acids (BA) suggest that dysbiosis may be accompanied by altered BA homeostasis, thereby contributing to the metabolic dysregulation seen in DM. Dogs develop naturally-occurring DM which may also be associated with dysbiosis and altered BA...

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PMID: 31316997
DOI: 10.3389/fvets.2019.00199

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