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Article

ETV6-related thrombocytopenia and leukemia predisposition

28 Jun 2019

Abstract excerpt

are responsible for a familial thrombocytopenia and leukemia predisposition syndrome. Thrombocytopenia is almost completely penetrant and is usually mild. Leukemia is reported in ∼30% of carriers and is most often B-cell acute lymphoblastic leukemia. The mechanisms by which ETV6 dysfunction promotes thrombocytopenia and leukemia remain unclear. Care for individuals with ETV6-related thrombocytopenia and leukemia...

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Acute Lymphoblastic Leukemia research
Acute Myeloid Leukemia Research
Immunodeficiency and Autoimmune Disorders

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31248877
DOI: 10.1182/blood.2019852418

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