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Advancing Functional Genetics Through Agrobacterium -Mediated Insertional Mutagenesis and CRISPR/Cas9 in the Commensal and Pathogenic Yeast Malassezia

26 Jun 2019

Abstract excerpt

Abstract Malassezia are a monophyletic phylum of 18 species of commensal/ pathogenic yeasts that are prominent in the mammalian mycobiome, and recently linked to risk of Crohn’s Disease. Malassezia are challenging to study... Malassezia encompasses a monophyletic group of basidiomycetous yeasts naturally found on the skin of humans and other animals. Malassezia species have lost genes for lipid biosynthesis, and...

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Identifiers

PMID: 31243056
DOI: 10.1534/genetics.119.302329

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