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Article

The Enamel Phenotype in Homozygous Fam83h Truncation Mice

6 May 2019

Abstract excerpt

Abstract Background Truncation FAM83H mutations cause human autosomal dominant hypocalcified amelogenesis imperfecta (ADHCAI), an inherited disorder characterized by severe hardness defects in dental enamel. No enamel defects were observed in Fam83h null mice suggesting that Fam83h truncation mice would better replicate human mutations. Methods We generated and characterized a mouse model ( Fam83h Tr/Tr )...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31060110
DOI: 10.1002/mgg3.724

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The Enamel Phenotype in Homozygous Fam83h Truncation MicePMID 31060110Read ↗

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