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Zika virus replication and cytopathic effects in liver cells

20 Mar 2019

Abstract excerpt

Zika virus (ZIKV) has emerged globally as an important pathogen, since it has been recognized as a cause of microcephaly and other neurologic processes and sequalae in newborns. The virus shares homology with Hepaciviruses and therefore may be a cause of hepatitis. We sought to characterize ZIKV replication in hepatocyte-derived cell lines. Huh7.5 and HepG2 cells were infected with ZIKV and replication potential...

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PMID: 30893357
DOI: 10.1371/journal.pone.0214016

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