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Article

Mutational load in carotid body tumor

1 Mar 2019

Abstract excerpt

BACKGROUND: Carotid body tumor (CBT) is a rare neoplasm arising from paraganglion located near the bifurcation of the carotid artery. There is great intra-tumor heterogeneity, and CBT development could be associated with both germline and somatic allelic variants. Studies on the molecular genetics of CBT are limited, and the molecular mechanisms of its pathogenesis are not fully understood. This work is focused...

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PMID: 30871634
DOI: 10.1186/s12920-019-0483-x

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