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Combined analysis and validation for DNA methylation and gene expression profiles associated with prostate cancer

4 Mar 2019

Abstract excerpt

BACKGROUND: Prostate cancer (PCa) is a malignancy cause of cancer deaths and frequently diagnosed in male. This study aimed to identify tumor suppressor genes, hub genes and their pathways by combined bioinformatics analysis. METHODS: A combined analysis method was used for two types of microarray datasets (DNA methylation and gene expression profiles) from the Gene Expression Omnibus (GEO). Differentially...

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Share to Epigenetics and DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30867653
DOI: 10.1186/s12935-019-0753-x

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