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Analysis of the characteristics and expression profiles of coding and noncoding RNAs of human dental pulp stem cells in hypoxic conditions

12 Mar 2019

Abstract excerpt

BACKGROUND: Human dental pulp stem cell (DPSC)-mediated regenerative endodontics is a promising therapy for damaged teeth; however, the hypoxic environment in root canals can affect tissue regeneration. In this study, we investigate the characteristics and possible regulatory mechanisms of DPSC function under hypoxic conditions. METHODS: ). DPSC proliferation and osteo/odontogenic differentiation potential were...

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PMID: 30867055
DOI: 10.1186/s13287-019-1192-2

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